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Kou-Gi Shyu Selected Research

pyrazolanthrone

1/2020Hyperbaric oxygen activates visfatin expression and angiogenesis via angiotensin II and JNK pathway in hypoxic human coronary artery endothelial cells.
5/2017Atorvastatin alleviates cardiomyocyte apoptosis by suppressing TRB3 induced by acute myocardial infarction and hypoxia.
1/2015Molecular regulation of the expression of leptin by hypoxia in human coronary artery smooth muscle cells.
3/2014Angiotensin II and the JNK pathway mediate urotensin II expression in response to hypoxia in rat cardiomyocytes.
1/2012Angiotensin II mediates urotensin II expression by hypoxia in cultured cardiac fibroblast.
2/2008The molecular regulation of GADD153 in apoptosis of cultured vascular smooth muscle cells by cyclic mechanical stretch.

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Kou-Gi Shyu Research Topics

Disease

19Hypoxia (Hypoxemia)
01/2020 - 08/2002
14Myocardial Infarction
11/2020 - 03/2004
13Atherosclerosis
12/2021 - 09/2005
9Hypertrophy
01/2019 - 04/2008
8Heart Failure
07/2020 - 03/2005
8Fibrosis (Cirrhosis)
09/2017 - 03/2010
7Infarction (Infarctions)
11/2020 - 03/2004
7Cardiovascular Diseases (Cardiovascular Disease)
04/2020 - 11/2007
7Neoplasms (Cancer)
05/2018 - 02/2003
6Hypertension (High Blood Pressure)
03/2021 - 12/2004
6ST Elevation Myocardial Infarction
05/2018 - 05/2011
5Stroke (Strokes)
05/2020 - 10/2010
5Ischemia
01/2019 - 08/2002
5Acute Coronary Syndrome
01/2019 - 01/2016
5Inflammation (Inflammations)
01/2016 - 07/2010
4Adenocarcinoma of Lung
11/2020 - 02/2003
4Coronary Artery Disease (Coronary Atherosclerosis)
05/2020 - 05/2006
4Hemorrhage
04/2020 - 05/2011
4Necrosis
10/2016 - 02/2008
4Cardiomegaly (Heart Hypertrophy)
03/2014 - 01/2005
3Neoplasm Metastasis (Metastasis)
11/2020 - 04/2006
3Atrial Fibrillation
04/2020 - 05/2017
3Vascular System Injuries
10/2016 - 02/2011
3Wounds and Injuries (Trauma)
03/2014 - 01/2006
3Cardiomyopathies (Cardiomyopathy)
09/2013 - 11/2006
3Body Weight (Weight, Body)
10/2010 - 01/2005
2Hyperglycemia
03/2019 - 02/2014
2Heart Diseases (Heart Disease)
03/2019 - 09/2010
2Non-ST Elevated Myocardial Infarction
01/2016 - 11/2014
2Pathologic Neovascularization
01/2012 - 06/2010
2Myocardial Ischemia (Ischemic Heart Diseases)
05/2006 - 10/2005
1Vascular Diseases (Vascular Disease)
01/2022
1Thrombosis (Thrombus)
04/2020
1Intracranial Hemorrhages (Intracranial Hemorrhage)
04/2020

Drug/Important Bio-Agent (IBA)

18Proteins (Proteins, Gene)FDA Link
11/2020 - 03/2004
13Small Interfering RNA (siRNA)IBA
01/2020 - 02/2008
8Messenger RNA (mRNA)IBA
05/2017 - 03/2004
8Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2006 - 02/2003
7DNA (Deoxyribonucleic Acid)IBA
01/2020 - 10/2008
6Oxygen (Dioxygen)IBA
11/2020 - 08/2002
6pyrazolanthroneIBA
01/2020 - 02/2008
6Atorvastatin (Lipitor)FDA Link
01/2019 - 03/2010
6EndoglinIBA
09/2017 - 03/2010
6Reactive Oxygen Species (Oxygen Radicals)IBA
01/2015 - 12/2008
6CollagenIBA
03/2014 - 09/2005
5ResistinIBA
01/2022 - 12/2008
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2017 - 02/2008
5LuciferasesIBA
01/2016 - 05/2012
5Angiotensin IIIBA
01/2015 - 04/2008
4Glucose (Dextrose)FDA LinkGeneric
01/2022 - 02/2014
4Discoidin Domain Receptor 2IBA
10/2016 - 09/2005
4Matrix Metalloproteinase 2 (Gelatinase A)IBA
10/2016 - 10/2008
4p38 Mitogen-Activated Protein KinasesIBA
10/2016 - 10/2008
42- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA
01/2016 - 12/2008
4myocardinIBA
07/2015 - 06/2010
4Myosin Heavy Chains (Myosin Heavy Chain)IBA
05/2015 - 06/2010
4Acetylcysteine (Siran)FDA LinkGeneric
01/2015 - 12/2008
4LeptinIBA
01/2015 - 11/2007
3MicroRNAs (MicroRNA)IBA
12/2021 - 05/2015
3Carvedilol (Coreg)FDA LinkGeneric
03/2021 - 01/2005
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2020 - 01/2012
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
04/2020 - 09/2014
3AnticoagulantsIBA
04/2020 - 12/2010
3Losartan (Cozaar)FDA LinkGeneric
01/2020 - 01/2012
3JNK Mitogen-Activated Protein KinasesIBA
05/2017 - 02/2008
3Valsartan (Vals)FDA Link
01/2016 - 05/2015
3Angiotensin Receptor AntagonistsIBA
01/2016 - 01/2012
3salicylhydroxamic acid (SHAM)IBA
05/2015 - 03/2005
3Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
03/2014 - 12/2008
3Phosphotransferases (Kinase)IBA
05/2011 - 12/2008
3C-Reactive ProteinIBA
09/2010 - 03/2006
3Angiopoietin-1IBA
01/2006 - 06/2003
2Long Noncoding RNAIBA
11/2020 - 01/2019
2Vitamin KFDA Link
04/2020 - 01/2016
2MetalsIBA
05/2018 - 05/2016
2TicagrelorIBA
05/2018 - 09/2014
2Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2015 - 12/2012
2CytokinesIBA
01/2015 - 07/2010
2urotensin IIIBA
03/2014 - 01/2012
2Serum Response FactorIBA
03/2014 - 06/2010
2Transforming Growth Factors (Transforming Growth Factor)IBA
03/2014 - 01/2014
2Brain Natriuretic Peptide (Natrecor)FDA Link
03/2014 - 06/2010
2Matrix Metalloproteinases (MMPs)IBA
12/2012 - 10/2010
2PPAR deltaIBA
09/2010 - 07/2010
2SB 203580IBA
04/2009 - 10/2008
2Pharmaceutical PreparationsIBA
04/2006 - 01/2005
1Nucleic AcidsIBA
11/2020
1Hypoglycemic Agents (Hypoglycemics)IBA
07/2020
1oxidized low density lipoproteinIBA
05/2020
1LDL CholesterolIBA
05/2020
1N(4)-oleylcytosine arabinosideIBA
04/2020

Therapy/Procedure

17Therapeutics
05/2020 - 08/2002
9Percutaneous Coronary Intervention
04/2020 - 02/2010
4Stents
04/2020 - 03/2007
4Aftercare (After-Treatment)
03/2019 - 01/2005
4Ligation
01/2019 - 03/2004
2Secondary Prevention
05/2020 - 01/2016
2Drug-Eluting Stents
05/2016 - 11/2014
2Cell- and Tissue-Based Therapy (Cell Therapy)
09/2014 - 02/2008
2Transplantation
02/2008 - 01/2006